Dating age equation xkcd
The jury is out on the justification of the "curse" of Awesome being Fantastic Racism; on one hand, superpowers aren't that much fun when the majority of the population believe suffocating you in your sleep is pest control.
On the other, it's not like All of the Other Reindeer will have an easy time burning you.
The "science" is called Astrobiology, the famous "science in search of a subject". You can keep up on the latest news, but for now if you want aliens, you are going to have to create them yourself.
Suggested reading includes The Encyclopedia of Science Fiction's entry on "Aliens", Steve Colgan's Worlds of Possibility blog, Life Everywhere by David Darling, The Science of Aliens by Clifford Pickover and Aliens and Alien Societies by Stanley Schmidt.[first use unknown, but goes back at least to 1940s]General SF term for an extraterrestrial or alien possessing human-level intelligence (see sophont).
The Curse That Cures can skirt this depending on the severity of the curse and the illness or injury it's curing as a side effect.
Relations between humans and Really Aliens are necessarily limited, since we have so little in common with them.Except for the Energy Beings, most seem to be hydrocarbon life forms, but methane breathers who thrive at -200 C will sometimes turn up.What they all have in common is that they are Really Alien.A character has some "terrible" curse placed on them (if they weren't born with it) that is actually pretty awesome.
Often, such characters will bemoan their fate and go to great lengths to be rid of the "curse" instead of taking advantage of whatever cool side effects the curse may have.Other times it's the "reward" for Heroic Willpower. The idea that the awesome is a curse may cause some forms of Internalized Categorism.